Taking high-dose vitamin D supplements for more than a year can significantly cut relapse risks and ease disability for people with MS according to a review of more than 30 clinical trials.
These benefits were observed in people who added the vitamin to their standard disease-modifying therapies, though the supplements had to be taken long term to be effective.
Long-term supplementation with a mid-dose also led to fewer relapses, the data showed. In contrast, add-on high-dose vitamin D taken for less than one year showed no significant differences. In terms of safety, vitamin D supplementation did not increase the risk of serious adverse events. Further large-scale trials are needed to explore this further.
Source: MS-UK
