Rituximab beneficial in secondary progressive MS

January 16, 2019 | Southmedia

Source Medicalxpress:  For patients with secondary progressive multiple sclerosis (SPMS), treatment with rituximab is associated with a significantly lower Expanded Disability Status Scale (EDSS) score and delayed progression, according to a study published online Jan. 7 in JAMA Neurology.

Yvonne Naegelin, M.D., from the University of Basel in Switzerland, and colleagues conducted a retrospective cohort study using data from patients with SPMS at three multiple sclerosis centers from 2004 to 2017. The EDSS score was compared for 54 patients with SPMS treated with rituximab and 59 patients not treated with rituximab; after propensity score matching, 44 pairs of patients were included. Patients were followed for up to 10 years.  Read on. 

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